Research & development

Research and projects

CieH runs and supports national and European research projects, from medical data infrastructure to personalised devices and space medicine.

Publications

Bioinnovative Center for Integrated Medical Data and Research in Bucharest

BioMedLakeActiveEU

A strategic initiative dedicated to developing biomedical research infrastructure, integrating medical data, and accelerating national collaboration in medical research. Total budget: RON 99,676,414, fully funded by the European Regional Development Fund.

The problem

Romania's large-volume medical and genomic data is fragmented across institutions, limiting research, development and innovation capacity and the transfer of results into clinical practice.

What we do

An integrated digital ecosystem for medical research based on clinical and genomic data is being built, through a Data Lake and HPC infrastructure for the secure collection, storage and processing of data from at least 30 partner medical units.

Impact

The project aligns with the EU's efforts to support STEP-compatible initiatives, aimed at developing strategic technologies, strengthening advanced digital infrastructure, and accelerating innovation with impact in healthcare.

Period

Jun 2026 – Dec 2029

Funder

Health Programme — European Regional Development Fund

Lead institution

UMF "Carol Davila" București

Partners

National University of Science and Technology POLITEHNICA Bucharest; Genomics Research and Development Institute; National Institute of Research and Development for Biological Sciences; Special Telecommunications Service

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Portfolio

All projects

CVDLINK

CVDLINK — A Federated Data Platform for Cardiovascular Disease

CVDLINK connects clinical, genetic and real-world data sources through an EU-wide federated platform to support diagnosis, risk assessment and personalised treatment of cardiovascular disease — responsible each year, across the EU, for over 6 million new cases and 1.8 million deaths.

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iBeCHANGE

iBeCHANGE — A Platform for Primary Cancer Prevention

iBeCHANGE develops a digital platform combining machine learning, health psychology and clinical guidelines to support lasting behavioural change and emotion management, aiming to reduce cancer incidence and mortality.

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RoMD-MedAI

RoMD-MedAI — Patient and Physician Perspectives on Artificial Intelligence in Healthcare

A project won through the UEFISCDI competition, coordinated by CieH in partnership with the National School of Public Health Management of the Republic of Moldova, dedicated to a strategic analysis of patient and physician perspectives on integrating artificial intelligence and medical-data processing into the healthcare systems of Romania and the Republic of Moldova.

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INNOV.STUD

INNOV.STUD — Innovative Education for UMFCD Students

CieH's first major FDI project built, in a single year, the practice bases for 3D Printing, Medical Simulation, Telesemiology and Big Data analysis, coordinated by Ș.L. Dr. Ștefan Busnatu, with a budget of RON 1,483,260.

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INOPRACT

INOPRACT — Innovative Development of Students’ Digital and Practical Skills

With a budget of RON 2,740,341, INOPRACT expanded CieH’s practice bases and established the Extended Reality (XR) hub, again coordinated by Ș.L. Dr. Ștefan Busnatu.

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FUTUREMED

FUTUREMED — Practice Bases for the Medicine of the Future

CieH's third consecutive FDI project further developed its existing practice bases and added a Medical and Health Humanities component, in collaboration with the University of Bucharest and UNATC.

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INNOVAMED-Praxis

INNOVAMED-Praxis — Integrated Advanced Medical Practice Platform

The project built a solid advanced-practice base for the Faculty of Midwifery and Nursing, through workshops dedicated to developing both basic and advanced skills in the field.

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INFOMED

INFOMED — Digital Information and Prevention During the COVID-19 Pandemic

CieH's first project, with a budget of RON 334,100, responded to the information emergency of the COVID-19 pandemic through digital communication and medical-education campaigns.

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Experimental Research Projects — 3D Printing Lab

Four experimental-demonstrative projects developed by the 3D Printing Lab in 2024, each exploring a frontier application of 3D printing in medicine.

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NextMEd

NextMEd — Developing and Integrating Emerging Technologies for Advanced Medical Education and Research

A project funded through the Institutional Development Fund (CNFIS-FDI-2025-F-0694), implemented by the Medical Simulation Hub and the e-Health, Big Data & AI Hub, dedicated to integrating emerging technologies and medical simulation into the training of students and medical staff.

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Scientific output

Publications

Articles published in international journals and papers presented at congresses by CieH members between 2022 and 2025.

29Articles

72Conference papers

3Awarded papers

4Years of scientific activity

29 results

Applied Sciences2025

3D Printing

Estimation of the Shear Stress (WSS) at the Wall of Tracheal Bifurcation

Nicoleta-Octavia Tănase, Ciprian-Ștefan Mateescu, Doru-Daniel Cristea, Corneliu Bălan

Estimation of the wall shear stress at the tracheal bifurcation, providing a theoretical and experimental basis for studying fluid flow in complex anatomical structures and for validating in-house biomechanical models.

2025;15(24):13055Open article

Cureus2025

Medical Simulation

Bioethics for Medical Students Using a Novel Concept for Patient Workshops

Cristian Toma, Aida Petca, Ioana G. Vișan, Alexandra Munteanu, Viorel Jinga

2025Open article

BMC Nephrology2025

e-Health, Big Data & AI

Chronic kidney disease in Romania: national adjusted prevalence, risk factors, and temporal trends in high-risk groups

Gabriel Ștefan, Octavian Andronic, Mihaela Daniela Balta, Ana Maria Alexandra Stănescu, Ștefan Busnatu, Viorel Jinga, Gabriel Mircescu

2025;26:623Open article

Frontiers in Immunology2025

e-Health, Big Data & AI

The pediatric nasal microbiome and its role in chronic ENT disorders: a narrative review

Adriana Elena Sîrbu, Gratiela Grădișteanu Pircalabioru, Diana Maria Deaconu, Octavian Andronic, Dan Cristian Gheorghe

2025;16:1699707Open article

Healthcare2025

e-Health, Big Data & AI

Digital Transformation of Medical Services in Romania: Does the Healthcare System Meet the Current Needs of Patients?

Ioana-Marcela Păcuraru, Ancuța Năstac, Andreea Zamfir, Ștefan Sebastian Busnatu, Octavian Andronic, Andrada-Raluca Artamonov

2025;13(20):2549Open article

Biomolecules2025

e-Health, Big Data & AI

Nanocomposite Biomaterials for Tissue-Engineered Hernia Repair: A Review of Recent Advances

Octavian Andronic, Alexandru Cosmin Palcau, Alexandra Bolocan, Alexandru Dinulescu, Daniel Ion, Dan Nicolae Păduraru

2025;15(9):1348Open article

Cureus2025

Medical Simulation

Impact of Standardized Patient Programs on Pre-clinical Medical Students' Clinical Readiness: A Narrative Review of the Last Two Decades

Cristian V. Toma, Aida Petca, Ioana G. Vișan, Alexandra Munteanu, Alexandru Ciudin, Viorel Jinga

2025Open article

Gels2025

3D Printing

Effect of Phosphate Phase Incorporation on 3D-Printed Hydrogel Scaffolds: Towards Customizable Bone Graft Materials

Andreea Trifan, Eduard Liciu, Andrei-Silviu Nedelcu, Mihai Dragomir, Doru-Daniel Cristea, Ciprian-Ștefan Mateescu et al.

Phosphate-containing 3D-printed hydrogel scaffolds aimed at customisable bone-substitute materials, with potential applications in tissue regeneration and reconstructive surgery.

2025;11(8):665Open article

Cancers2025

e-Health, Big Data & AI

Gut Microbiome Alterations in Colorectal Cancer: Mechanisms, Therapeutic Strategies, and Precision Oncology Perspectives

Miriam Tudorache, Andreea-Ramona Treteanu, Gratiela Grădișteanu Pircalabioru, Irina-Oana Lixandru-Petre, Alexandra Bolocan, Octavian Andronic

2025;17(14):2294Open article

Valorisation

Technology transfer and innovation

CieH supports its members' innovation activity: from obtaining patents and protecting intellectual property, to technology transfer into industry and facilitating start-up or spin-off ventures born out of university research.

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CieH supports UMFCD researchers in building and running national and international projects.

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